Liver transplantation for hepatoblastoma

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Pediatric liver transplantation for hepatoblastoma.

Hepatoblastoma is the most common pediatric liver tumor and is usually diagnosed before five years of age. Treatment consists of a combination of chemotherapy and surgery, with the goal being attainment of complete local control by surgical resection and eradication of any extrahepatic disease. Neoadjuvant chemotherapy is utilized and is often beneficial in rendering tumors resectable; however,...

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Liver transplantation for hepatoblastoma. The American experience.

The current role of liver transplantation in treating malignant tumors of the liver is uncertain, except for select histologic types. Pooled data on the results of liver transplantation in 12 children with hepatoblastoma is presented here. One half of the children are alive 24 to 70 (44 +/- 19) months after transplantation with no evidence of recurrence. Three patients (25%) died of tumor recur...

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Liver transplantation in the management of unresectable hepatoblastoma in children.

Complete surgical resection is essential to long-term survival in children with hepatoblastoma. We present the guidelines from the Children's Oncology Group (COG), liver tumor study group of the Societe Internationale Oncologie Pediatrique (SIOPEL), and German Pediatric Oncology Group (GPOH) for early referral of children with potentially unresectable hepatoblastoma to a specialty center with e...

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Recurrence of hepatocellular carcinoma as a mixed hepatoblastoma after liver transplantation.

BACKGROUND Hepatoblastoma is an exceptional cause of primary malignant liver tumour in the adult. PATIENT The case is reported of an adult patient transplanted for alcoholic cirrhosis complicated by multifocal hepatocellular carcinoma in whom a recurrence in the form of a mixed hepatoblastoma invading the whole transplanted liver developed three months after liver transplantation. METHODS C...

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ژورنال

عنوان ژورنال: Liver Transplantation

سال: 2008

ISSN: 1527-6465,1527-6473

DOI: 10.1002/lt.21586